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Nicotinamide is a precursor of NAD+, the central cofactor of energy metabolism

It has been one of the most extensively studied peptides in preclinical gastroenterology and tissue biology research, with over 100 published animal studies examining its effects across multiple organ systems

It gains its effectiveness from both its ability to bind with copper and its ability to up and down-regulate a minimum of 4,000 different genes

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Results In both groups, mean serum vitamin B12 increased after 30 days of treatment and was maintained up to 90 days